Detecting painkillers in the poison of anemones

According to two articles published in the scientific publications Toxins and the Journal of Biological Chemistry, scientists at the Russian Academy of Sciences found that unique anemones in the venom of the anemones help inhibit the activity of Pain receptors and reduce inflammation.

It is important that unlike the components of existing painkillers, these analgesic proteins are not addictive.

Anemone is one of the earliest carnivorous species.

Anemone is one of the earliest carnivorous species. It is believed that their ancestors appeared on Earth more than half a billion years ago. When passed by the poisoned anemone tentacles, especially from some anemones (for example, Metridium senile and Urticina eques), the fish and other creatures become immobile and become Good prey of anemones.

Russian scientists analyzed the toxins released by Metridium senile and Urticina eques , found to contain interesting proteins named Ms9a-1 and Ueq 12-1. This is the TRPA1 receptor inhibitory protein responsible for pain sensitivity and some other sensations as well as the development of inflammatory response.

According to the scientists, on the basis of these proteins can create analgesic and anti-inflammatory drugs that work at the correct points on the body.

The proteins tested on mice proved their effectiveness. Now only clinical trials are conducted on humans.