Find out how to recover memory

Most people, the elderly, do not know that their memory has deteriorated. Experts Heidelberg University (Germany) has found a way to stop being forgotten because of age but only in . mice.

They do this by inserting a yeast into the rat brain to close and open specific genes. It is the enzyme with the symbol Dnmt3a2 that medical researchers have successfully studied, belonging to the type of DNA-metiltransferazine that regulates the activity of the gene and changes its structure. That way affects the memory of the mouse.

In a new study, German scientists injected the hippocampus (the bulge in the lateral ventricular part) in the rat brain with a harmless version, encoding the Dnmt3a2 gene. This brain region is responsible for converting short-term memory into long-term memory. Thanks to the virus carrying the genetic material, they introduced the necessary genes into the rat brain.

Picture 1 of Find out how to recover memory
Men Dnmt3a2 may be a new way to improve memory in the elderly.

To understand how the 'transformation' of DNA expressed on memory occurred in mouse brains, scientists tested them. They let the rats get acquainted with 2 objects and the next day swapped out one of the 2 objects. The young mice stared intently at the objects that had been displaced, and the old mice stared at both objects, as if they were both new to them for the first time.

For older mice that have been fermented into the brain, the time they spend to observe displaced objects is less than 30%. This proves that thanks to yeast introduced, they recalled what they had seen before. Hilmar Bading, author of the study, said that if men inject into the brains of old mice, their memory is not inferior to those of young mice.

To re-examine the results, the scientists inserted the old mouse brain with only half the amount of yeast needed. This time their memory was as bad as the normal old mice in the control group. From the results, the researchers concluded that memory is directly proportional to a certain amount of yeast within a certain limit.

Currently, no drugs have been found to increase the levels of Dnmt3a2 in the human brain. However, researchers believe that there will definitely be a way to help the brain maintain this enzyme in an active state and force it to work, so that the elderly recover their memory as they were when they were young and will benefits to society. For example, it is possible to extend retirement age because many people have reached retirement age but physical health is very good.

Bading and colleagues continue to study ways to prevent memory decline and they recommend that while no specific measures have been found yet, regardless of age, live actively because of the activity. The brain is also a way to prevent memory impairment.