Implants can kill up to 98% of bacteria

Scientists from the National University of Science and Technology (NUST MISiS), together with their Czech and US colleagues, have developed a new implant material that helps prevent post-surgical infection.

The material was revealed to be a combination of platinum and iron nanoparticles that can kill up to 98% of bacteria within 12 hours after transplanting.

In fact, bacterial infections occur in 1 to 4% of cases after surgical intervention. In cases of patients with fractures requiring transplants, the likelihood of bacterial infections causing infection is up to 30%. If an infection occurs, the patient should often be treated by a physician. In milder cases, patients also need antibiotic treatment.

Picture 1 of Implants can kill up to 98% of bacteria

The new implant material from scientists from Russia is said to be capable of destroying a wide range of bacteria.

During treatment, the patient's body is under great pressure. In addition, the disease-causing bacteria are rapidly developing antibiotic resistance, and many people are severely allergic to antibiotics.

Under this situation, NUST MISiS scientists and their colleagues developed a new implant material with metal nanoparticles , which inhibits the growth and spread of pathogenic bacteria. without any inhibitory effect on lymphocytes or immune system cells.

"We implanted platinum and iron ions into a matrix, which is a TiCaPCON biocompatible coating (titan-calcium-phosphorus-carbon-oxygen-nitrogen). As a result, metal nanoparticles are stimulated. a few nanometers above the coating surface. When exposed to the surface of the material, the bacterial film can be destroyed, " said Viktor Ponomarev, lead author of the study.

In addition, when implants are sterilized with ultraviolet radiation, a large number of free radicals are created, which also leads to bacterial death.

According to the authors of the study, even at the experimental stage, the newly developed material destroyed 98% of bacteria in 8-12 hours, including bacteria such as Staphylococcus Aureus, Epidermal Staphylococcus Aureus, Escherichia. Coli and Klebsiella Pneumoniae.

The scientists are currently looking at the tests of the samples collected and reveal another promising application for newly developed materials that could be to create future water filters.

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Update 20 November 2019
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