Most people with cancer are genetically predisposed?

Scientists at the University of New South Wales (UNSW) and Western Australia have just published a breakthrough scientific research to explain why many types of cancer are genetic , passed from one generation to another and right in the family members.

The information, published in The Telegraph on Aug. 16, said the team found that changes that were difficult to detect outside the cancer-resistant gene could absorb an amount of birth. Inefficient chemistry makes this gene unable to "function" normally.

This is the main reason that increases the risk of developing deadly tumors in cancer.

Until now, scientists have been able to identify changes within MLH1 , which prevent cancer, that can be transmitted from generation to generation and enhance the risk of development. tumors in the intestine, uterus and some other types of cancer, accounting for up to 80%.

However, researchers are also trying to find out why 30% of families with a history of cancer do not show changes in their MLH1 gene system.

The discovery of a decisive effect on the structural change of MLH1 gene, which can transmit cancer, is based on research from families of many people with this life-threatening disease.

The results published by the University of Western Australia for a family with a woman with stomach cancer and two others with bowel cancer, resulted in both of her five grandchildren suffering from cancer. letter on.

Genetic tests cannot detect any general changes in MLH1 genes to explain why the disease could be transmitted.

However, the scientists found that MLH1 has undergone minor biochemical changes and this is how it can spread and increase the risk of cancer for at least three generations.

The change is also related to the DNA sequence during the "start" of the MLH1 gene and shows that the system has sent false signals.

This mistake has caused MLH1 to absorb biochemical amounts known as methylane , which stands higher than DNA and has the function of "turning off" MLH1 so that it cannot prevent cancer.

Previously, in families with a history of cancer related to changes in MLH1, all members were assigned regular medical tests to detect early signs of cancer by It is difficult for doctors to diagnose who is having genetic abnormalities in the body.

However, now, scientists can know the changes in MLH1 can create cancer risk and only those members who have changes in this gene system will need regular medical examination. piercing.