New findings by US scientists in the treatment of Parkinson's disease

In a recent study published in the American Journal of Science, scientists at Northwestern University in the United States discovered a cause of brain cell death in Parkinson's patients and the use of anti-substances. oxidation to prevent brain cell damage.

Previous studies have shown that brain cell death involves two structures in the cell, called mitochondria and lysosomes.

The accumulation of oxidized dopamine in brain cells causes some to be broken.

On this basis, chairman of Northwestern University's Department of Neurology, Dimitri Kranic and colleagues, through the study of brain cells from Parkinson's patients, found a chain reaction of dysfunction. These two cell structures, caused by the accumulation of a defective neurotransmitter , are called oxidized dopamine .

The accumulation of oxidized dopamine in brain cells causes some to be broken, thus also damaging the mitochondria and these damaged cell structures accelerate the accumulation of faulty neurotransmitters. The result of such a faulty cycle has resulted in brain cell death.

The team at Northwestern University has begun to seek to interrupt the process. One of the key strategies effective in experiments is early treatment of brain cells in this process with specific antioxidants.

Kranic said this approach could weaken or prevent the effects of this process on dopamine neurons in humans, thereby developing new therapies for Parkinson's disease in future.

If the patient is diagnosed early, treatment with antioxidants can disrupt the above harmful cycle.