No fingerprints - a rare disorder

Imagine how much trouble you would have with paperwork without fingerprints. However, it is not the last difficulty because such a condition is also a manifestation of a rare disease.

Rather, two diseases at the same time: Naegeli syndrome and network disorders of skin pigmentation. This is a type of genetic disease and scientists think they may have initially found the genetic code responsible for the disorder.

Researchers at the Technion Institute, Israel at Haifa and Thomas Jefferson University in Philadelphia believe that the protein keratin number 14 is responsible for both of these diseases (protein keratin is a fibrous protein that forms the muscle horn tissue. like nails .)

For some people, having no fingerprints does not affect life very much. Some people find it more difficult to hold things, and some other activities such as dealing cards, books . are also more difficult. These people of course have a lot of trouble finding jobs, especially those that require high security.

However, with signs of no fingerprints is thickening of the skin on the palms and feet. Patients also experience many abnormalities in the development of teeth, hair and skin, where pigmentation may occur in patches or irregularly. Most dangerous is some skin problems that make them unable to sweat normally. And according to Professor Eli Sprecher of Technion School, co-author of a study on this situation in the October issue of the American Journal of Human Genetics, this is the most serious effect of this disease.

The fingerprint image of a person is taken with the ray of the ray
Micro X-ray machine (Photo: Nationalgeographic)

Because they cannot reduce their body temperature, they may faint because of excessive body heat. For them, sport is a tough challenge. Children can be very passionate about swimming but have to give up because cold water does not help the body reduce excessive heat gain. People with this symptom often have to be very careful to keep their bodies cool, and there are always ice packs available, and often have to be in air-conditioned rooms year-round.

Unfortunately, so far there is no solution for this disease. But finding its culprit, protein keratin 14, may be the key to helping us better understand other dangerous diseases. Professor Gabriele Richard, a genetic expert of Thomas Jefferson, said that keratin clearly plays a very important role in developing skin and forming fingerprints in the fetus.

The researchers are also investigating whether there is a link between keratin and the programmed cell septic processes. Information from here can help solve many skin disorders. This septic process is how cells destroy themselves once its useful life is over. In cancer cells this process does not work, leading to the continued existence and development of "obsolete" cells.

According to today's Knowledge, National Geographic, Vnexpress