Revealing the culprit causing

Almost every woman is well aware that their "pear" pair tends to sag more quickly than expected.Currently, scientists have discovered that the biological clock is the culprit that actually causes breast tissue to age faster than the rest of the body.

According to researchers from the University of California (USA), an integrated biological clock in our genome helps reveal why people age and how it can slow this process.

Steve Horvath, a professor of genetics and research team member, said: "To combat aging, we first need to have an objective way to measure that process. Identifying Biological markers of time throughout the body take up to four years, our goal in creating biological clocks is to help scientists improve their understanding of the culprit that has accelerated or slowed. re-aging process in humans ".

According to the biological clock, aging breast tissue is about 2-3 years faster than the rest of the female body.(Photo: Corbis)

To create this biological clock, Professor Horvath and colleagues focused on the natural methylation process and altered DNA . They screened data from 121 previous studies of methylation in both human and healthy tissue. Gathering information from nearly 8,000 samples of 51 types of tissue and cells extracted from all over the body, Horvath's group charted how aging affects the level of methylation of a person from birth. to 101 years old.

While the biological age of most samples corresponds to their age according to their birth date, the remainder has a large difference. For example, Professor Horvath discovered, aging healthy breast tissue is 2-3 years faster than the rest of the female body. But if a woman has breast cancer, healthy tissue adjacent to the tumor will be "older" on average for the rest of the body for up to 12 years. The biological clock also ranks the tissue for aging tumors more than healthy tissue for up to 36 years.

The speed of the biological clock also increases or decreases depending on the age of a person. Specifically, it will "run" faster from infancy to adolescence, and then gradually decrease to a constant rate when people turn 20.

Professor Horvath also looked at pluripotent stem cells - reprogrammed adult cells into embryonic stem cells, which can transform them into any form of cell in the body and continue to divide indefinitely."Our research shows that all stem cells are in the form of newborns. More importantly, the process of turning a person's cells into pluripotent stem cells has adjusted copper." The biological pool of cells reaches zero ".

In principle, discovering on the function only, scientists can reverse the biological clock of the human body and restore it to the original 0 state. Professor Horvath is expected to continue to study whether the body's aging clock stops the aging process or increases the risk of cancer.