Tamiflu: New regimen to treat H5N1 flu

Vietnam, Thailand and Indonesia were selected to adjust Tamiflu treatment regimen in patients with A / H5N1 type influenza virus and other serious flu.

Drugs Tamiflu (Photos: media.noticias)

The new regimen is currently being tested in the framework of the 'Tamiflu resistance study plan' organized by the US-based Family Health Organization.

At a meeting held on March 16 in Hanoi with the participation of scientists from Thailand, Indonesia, Vietnam, the UK and the US, experts agreed to establish a research network. Clinical rescue of flu in Southeast Asia.

In this network, Vietnam, Thailand and Indonesia were selected as the trial sites for adjusting the Tamiflu treatment regimen in patients with A / H5N1 type influenza virus and other serious flu.

The trial of doubling the Tamiflu treatment dose in patients with H5N1 flu is expected to increase from 150mg to 300mg / day / person.

This is a pilot program to adjust influenza regimens, initiated by the World Health Organization (WHO), the Family Health Organization and the British University.

The decision to double the Tamiflu dose was based on an animal dose-boosting test showing that the influenza virus was effectively controlled, while in some influenza A / H5N1 patients treated Tamiflu was on track. map (150mg / person / day), the virus density does not decrease.

5 facilities of Vietnam selected to participate in experimental treatment are the Institute of Clinical Medicine and Tropical Diseases, National Hospital of Pediatrics (Hanoi), Children Hospital I, II and Tropical Hospital ( HCMC). On the basis of the test results with a support budget of about 2.5 million USD, WHO will make a new recommendation on the Tamiflu flu treatment regime for countries.

It is known that in Vietnam so far has recorded 4 cases of H5N1 patients resistant to Tamiflu.

Thu Linh