The boy carries female chromosome 46 XX

Having testicles, but since childhood, he suffered from urine falling down his legs every time he went to the toilet, a 20-year-old boy examined at Binh Dan Hospital discovered chromosome 46 XX.

Masculine, solid appearance, Khang was born with an abnormal sexual organ , only one left testicle left. At the age of 13, Khang started breaking his voice, appearing signs of puberty like his boyfriends of the same age. Feelings with women, Khang still has a normal girlfriend. Fear of birth defects in his genitals, the boy went to the male doctors.

Doctor Mai Ba Tien Dung, Head of the Department of Male Studies at Binh Dan Hospital, said the examination results showed that the beard and pubic hair of men were distributed in a male style.Urinals lower the penis root. The large left scrotum, a shape unlike the testicle, does not see the testicle in the right scrotum. Testosterone hormone levels of patients are within normal limits, with prostate. However, the chromosome and gene test results are 46 XX , with the SRY gene.

" Usually men carry the chromosome 46 XY. In this case, after the two gonadectomy, biopsy results show that it is testicular tissue, so it can be confirmed that this male sex patient is infected. chromosome is 46 XX ", Dr. Dung shared.

The chromosome of the patient results in 46 XX.

Doctors edit the urethra and penis to help patients urinate normally and lower the two gonads to the scrotum. Currently the patient already has a penis and two testicles but is unable to have a baby because the spermatogenesis has degenerated, unable to produce sperm. Luckily, the endocrine function of the testicles is still good because there are still male hormones secreted by testosterone.

Dr. Le Vu Tan, Department of Male Studies said that gender development disorder 46, XX male is a rare disease with a reported rate of about 1 / 20,000 newborn babies. Clinical symptoms may be heterogeneous, the external genitalia is usually completely male in 90% of the male 46 XX cases. These cases are usually diagnosed after puberty when there are signs of hypogonadism, gynecomastia or infertility.

Most of these cases are due to the passage of the Y chromosome into the X chromosome, which occurs after a short branch recombination of X and Y chromosomes during fecal excretion (with the SRY gene). These cases are often slow in height, normal mental development and congenital anomalies such as low urinary closing, hidden testicles.

Doctors recommend that all abnormalities of genital organs should be examined early to be intervened and timely improved.