Create genetically modified version of MERS-CoV virus

Spanish scientists claim they have created a genetically modified version of the Middle East Respiratory Syndrome (MERS-CoV) strain, which can be used as a basis for producing a vaccine. Please be safe and effective.

>>>Situation solution for people infected with MERS-CoV

In the work published Sept. 10, the scientists said the genetically modified virus, scientifically known as rMERS-CoV-E, could infect cells to neutralize its ability to spread. other tissue and cause disease.

This genetically modified virus can only replicate itself with a certain number and then produce enough antigen to immunity the host. It cannot infect other people, even those who have close contact with the vaccinated person.

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Scientists synthesized infectious asexual chromosomes in the gene map of the MERS virus and then transplanted this chromosome into an artificial chromosome of the virus to study the infectious effect, the ability to multiply. copies and re-infection of the virus in the cells of human transplanted viruses. They found that gene mutations in so-called membrane proteins could help the virus copy their genetic material, but could prevent the virus from infecting other cells.

MERS-CoV virus is considered a "relative" of the acute respiratory syndrome Syndrome (SARS) virus, the virus that caused disease in Asia in 2003 with 8,273 cases of infection and a death rate of 9%. .

Like SARS, the MERS-CoV virus also causes flu symptoms and is thought to be transmitted from animals to humans, but more dangerous than SARS because it can cause kidney failure and the death rate of infected people up to 51 %

MERS-CoV was first discovered in September 2012. As of the beginning of this month, the World Health Organization (WHO) has confirmed 52 deaths from new viruses, approximately 50% of infected people worldwide (110 cases). This disease is currently the most raging in Saudi Arabia.