Detecting positive lung response with bitter taste

According to the researchers, when we inhale a bitter air flow, the lungs will understand that this is a message that the air outside is easy to breathe, stimulating the lungs' receptors to feel comfort and opening airways, this finding could lead to finding new asthma medications. This report was published in Nature Medicine on October 24, 2010.

The bitter taste receptor is abundant on the human tongue, including smooth muscle tissue surrounding the trachea tubes leading to the lungs, according to a report from the University of Maryland and Johns Hopkins University in Baltimore, United States. States Experiments on reproductive mice have asthma after being inhaled with a bitter taste of quinine, resulting in clear airway passage and easy breathing mice that have led to the development of antidepressant drugs for albuterol.

The bitter taste receptor in the muscles of the lungs is the target of new asthma medicines, including drug molecules that stimulate the activity of organs that sense the bitter taste in the lungs , according to Mathur. Kannan, a pharmacologist at The College of Veterinary Medicine at the University of Minnesota, near St. Paul, Minnesota, USA.

The positive response to the bitter taste is still somewhat confusing. In our mouths, the bitter taste receptor acts as part of the body's mechanism to counteract the entry of toxic substances. Cells in the upper part of the respiratory tract also have a bitter taste receptor, according to scientists' reports in early 2010. But there, the bitter taste receptor can trigger a reaction. " out, out ", stimulate the cilia of the respiratory tract to push any nearby object up or out. Therefore, it seems reasonable that muscles controlling airflow into the lungs shrink when stimulated by potential toxins, according to Stephen Liggett, who works at the University of the Maryland School of Medicine, Baltimore, United States. States

Previous research has shown that some molecular signals produced by bacteria also activate receptors for bitter taste . Perhaps respiratory passage helps prevent lung infections.

" When you feel a lot of stickyness leads to suffocation ," liggett said. " You will die before you get antibiotics. "

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Ho Duy Binh
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