Detecting the gene makes the heart broken

Scientists have discovered a dangerous gene to the human heart because it prevents the body from recovering from injury.

According to experts, the Meis1 gene is the culprit that prevents the recovery of the heart.

Meis1 gene usually affects right after birth to prevent dividing heart cells from losing control. However, this gene also hinders the adult's heart to recover and repair itself after injury, such as heart attacks.

The results of laboratory tests show that the removal of Meis1 gene will re-activate the recovery process in the hearts of adult mice without harming the functioning of the agency.

Meis1 gene prevents heart cells from dividing, thus obstructing the left
adult hearts recover from injury. (Photo: Corbis)

Experts believe that the discovery could lead to new, breakthrough treatments for heart failure - a common consequence after heart attacks.

Dr. Hesham Sadek, head of research from the Southwestern Medical Center of the University of Texas, stated: "Meis1 is a transcription factor, acting as a software program capable of controlling function. The power of other genes.

We found that Meis1 controls many common genes that act as a brake for cell division. Therefore, Meis1 can be used as an on / off switch to make adult heart cells divide. If successful, this ability could bring a new era in heart failure treatment. "

In 2011, Dr. Sadek's group once found that the hearts of newborn mammals have a strong resilience after suffering damage. However, when this animal grows, it will quickly lose the ability to repair "errors" in the heart.

So, according to Dr. Sadek, the recognition of Meis1's "culprit" could bring a new approach to the treatment of heart failure testing. Current therapies focus on stem cells.