First sketches the genome map of a family

The website of the latest issue of the American Journal of Science and Technology shows that for the first time, American scientists have successfully outlined the entire genome sequence of a family of four members.

Successful delineation of the genome based family unit will provide valuable information in genetic research and related diseases.

Scientists say they have collaborated with a genome sequencing company to outline the entire genome sequence of a couple and two children. The two children in this family all suffer from miller and disease syndrome primary ciliary dyskinesia (PCD).

Through genome sequencing for these family members, scientists have identified exactly four genes that are associated with miller syndrome.

David Gallas, a member of the research team, said: "We can observe all gene mutations, including genetic traits that are relatively rare and can constitute parts of chromosomes. This plays a key role in studying related diseases. '

According to scientists, sequencing the genome of all family members can gain a lot of genetic information, and thereby distinguish rare gene mutations and find one. Exactly how genes are linked to some diseases. Moreover, it can be through collation to identify some errors in the process of genome sequencing, to help improve accuracy in the sketching process.

In particular, in the process of sketching scientists, for the first time, the mutation rate between two generations is predicted. Specifically, scientists have discovered, the rate of gene mutations from parental life to children is only half that of previous scientific predictions.

Scientists say that sequencing the family genome will become a new tool in gene research and treatment later.