Found infertility genes in men

A faulty gene could be the reason why men are infertile, scientists say.

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One in seven couples in the UK has problems with having children and infertility in men accounts for half of these cases.

The cause of this situation is not known yet, but a new study shows that faulty genes play an important role in some infertility cases in men.

The NR5A1 gene has a protein that plays an important role in the development of physiological problems and when this gene fails, it leads to defects in the reproductive organ. But how it plays in infertility is currently not being studied.

Dr. Ken McElreavey, French Pasteur Institute, said: ' Many genes are very important in sperm production but it is surprising that there are a number of single genes that can cause sperm production to fail. '.

His team looked at the NR5A1 gene in 315 men who were treated for infertility, all of which had very poor sperm quality and quantity. Of these, 7 have mutations in the NR5A1 gene. Published in American Gen Magazine, Dr. Anu Bashamboo said this mutation affects fertility genes, altering the level of sex hormones.

This suggests that although the defect is not visible to the naked eye, mutations can have a negative effect on the reproductive role in humans.

' We estimate that about 4% of men have poor sperm quality due to the presence of the dough-producing NR5A1 gene ,' Dr. Bashamboo said.