French suspended circulation Nizoral tablet form

The French Medical Product Security Agency (Afssaps) has issued a statement about the suspension of Nizoral's circulation license (containing the safe agent of theoconazole) in the form of a 200 mg tablet produced by Janssen-Cilag because of its risk of toxicity. for the liver.

Nizoral tablets are indicated for the prevention of parasitic fungi such as ringworm, yeast, binary fungi, preventive treatment for patients with reduced resistance, which can lead to fungal infection . Nizoral tablets licensed in France since 1982 and used quite popular in many countries around the world. According to Afssaps, the proportion of patients with side effects leading to liver toxicity and Nizoral intoxication is higher than other antifungal drugs. The use of Nizoral cream, shampoo to apply on the skin, bathing . is not warned because the amount of active ingredients capable of damaging the liver is very low.

Because Nizoral tablets are circulated in many other European countries, Afssaps said it has sent documents to re-evaluate the balance of benefits - risks of this drug. While waiting for the official results, Afssaps suspended the circulation license of Nizoral tablets of 200 mg and began recalling this product on the market from July 11, 2011.

In addition to the antifungal effect, Nizoral tablets are now also indicated for patients with Cushing's syndrome (a condition that enhances primary adrenocortical function due to tumors or hyperplasia, causing excessive secretion of glucocorticoids). Patients with this syndrome may die if not treated properly. Therefore, before the official assessment results can be obtained, the doctor can still prescribe Nizoral tablets to Cushing patients.

Some drugstore owners in Ho Chi Minh City said that Nizoral products in Vietnam market have 3 types: shampoo, cream, and 200 mg tablets. 200 mg tablets sold in Vietnam market are produced in Thailand, the retail price is around 9,000 VND / tablet.

Dermatologists in Ho Chi Minh City said that Nizoral, a 200 mg tablet of Janssen-Cilag, is a very familiar medicine and is preferred by doctors in the country to treat ringworm and inflammation. seborrheic skin; Some cases are used for pulmonary disease in the lungs, and fungi inside the body.