Genetically modified order helps detect cancer early
According to a study published in the Journal of Cancer Discovery (the latest issue of the American Cancer Research Association), scientists say the order of genetic modification in cancer cells is the key to diagnosis. Early diagnosis and identification of drugs to treat this disease.
The co-author of the study, Associate Professor Raymond Cho from the Department of Dermatology at the University of California, San Francisco (UCSF), said: 'We realize that every cancer is a collection of genetic changes. , so that we can identify changes that occurred earlier as well as changes after analyzing the genetic structure of samples of patients. '
A cancer patient is in the treatment phase.The team focused on TP53 - a cancer-causing mutation gene - that occurs in epithelial and ovarian cancer cells.
They analyzed additional copies when TP53 developed and found complex changes in TP53 that occurred earlier in most cases of cancer, not later, just as they had expected. guess.
According to the study, the ability to accurately identify genetically modified sequences will help scientists know which changes lead to early or changing cancer-predictive infections that produce real malignant tumors. receptor, so can prevent early or timely treatment of this disease.
According to Associate Professor Cho, the study is the result of a collaboration between UCSF, Oregon University of Science and Medicine, University of California at Berkley and Samsung Advanced Technology Institute.
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