Hands-on is decided by genes

(a genetics study) - A genetic study has identified a biological process that influences whether we will be left-handed or right-handed.

Scientists at the Universities of Oxford, St Andrews, Bristol and Max Plank Institute in Nijmegen, the Netherlands, found a correlation between hand-in-hand status and a network of genes associated with left asymmetry - right in developing embryos.

'The genes involved in the biological process through an early embryo move from being a circular mass of cells and becoming a developing organism to the left and right that has been formed' , author William Brander of the study, a graduate student at the MRC Functional Genomics Unit at Oxford University, said.

Researchers believe that genes can also aid in the formation of right-to-right differences in the brain, thus affecting the forehand. They reported the discovery in PLoS Genetics.

Humans are the only species that exhibit a strong handedness trend, with about 90% right-handed. The cause of this trend is still a mystery.

Researchers led by Dr. Silvia Paracchini at the University of St Andrews were interested in finding out which genes could influence left or right handed, to gain a deeper understanding of the origins. multiplication and evolution of this handed-handed condition.

The team made a model of a Genome-wide association study (GWAS) to determine if there are any common gene variants related to human preference for hand use. Left or right hand or not.

The most closely related, statistically significant variation with the right-handed status in the gene is PCSK6, a gene involved in early and right-set up in a developing embryo .

The researchers then used all of the knowledge gained from previous studies on the effects that PCSK6 and similar genes caused in mice to explore more about biological processes. mandarin

Breaking PCSK6 in mice causes asymmetric left and right defects, such as abnormal positions of organs in the body. For example, they may have a heart and stomach on the right and the liver is on the left.

The researchers found that variations in other genes that cause left and right defects when interrupted in mice are much more likely to relate to hand skills than we anticipate.

While the team identified the role of the gene in relation to the left-hand formation from the right in embryonic development, William Brandler warned that the results of this study do not adequately explain the Full-handed change in some people. He said: 'Like all aspects of human, natural and educational behavior, go hand in hand. The development of handedness comes from a combination of genes, environment, and cultural pressure to match right-handedness. "