Having type 2 diabetes is more prone to blood cancer
According to a study published in the July 14 issue of Nature Genetics, DNA deficiencies in people with type 2 diabetes may explain why they are more likely to develop leukemia than others.
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After studying blood samples from nearly 7,500 people, including 2,200 people with type 2 diabetes, researchers from the French National Center for Scientific Research and Imperial College London (UK) discovered the cancer. Blood letters related to cell mutations, also known as asexual mosaic (CMEs) cases . These mutations may lead to an abnormal number of cloned or cloned cells missing genetic code.
According to this study, among people with type 2 diabetes, CMEs are 4 times higher than healthy people. In normal people, CMEs are rarely seen in young people but are common in the elderly.
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According to previous studies, about 2% of people over the age of 70 suffer from this mutation, making them 10 times more likely to develop blood cancer than their younger counterparts.
According to Philippe Froguel of Imperial College London, the lead researcher, the finding may explain why people with type 2 diabetes are more likely to develop leukemia. Previously, the medical community knew the relationship between type 2 diabetes and leukemia and blood cells, but the cause was unknown.
Froguel said in the future, genetic testing could help identify patients with type 2 diabetes that are susceptible to CMEs. These patients will be closely monitored for early detection of symptoms of leukemia and can be treated with mild chemotherapy.
According to the World Health Organization (WHO), 347 million people worldwide have diabetes, of which about 90% are type 2 diabetes - at high risk of kidney, eye and heart diseases. Diabetes is a disease because the body cannot metabolize glucose in the blood with insulin. People who are obese and sedentary are more likely to develop type 2 diabetes, which usually occurs during adulthood.
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