Humans will be able to use pig heart instead of human heart thanks to this genetic technique

Biologist Hiromitsu Nakauchi of Stanford University said that pig cells and sheep cells normally have only 0.5% similarities to human cells but with genetic modification techniques and cell transplantation Root, similarity can be up to 40%.

Currently, the issue of the supply of organ donations to make transplant surgeries is becoming more and more apparent in many parts of the world. That makes scientists have to find a new way to solve this situation with the current method still creating conflicting opinions: culturing human organs inside other organisms from stem cells. . However, there are currently 3 different research groups deploying this idea in the US and initially there have been certain advances.

This idea is thought to be related to a hybrid technique that caused a lot of controversy called Chimera - based on the name of the famous monster in Greek mythology that has the previous part of the lion, the latter part of the reptile and the tail is a snake.

In addition, there is a goat head and dragon head on its back - this method aims to create certain body parts or a living individual hybrid between humans and some specific animals in the lips. School lab for the purpose of research and healing.

The image depicts the Chimera monster in legend.

Although there have not been any official reports on the results of this idea, scientists at the Massachusetts Institute of Technology for the past year have had 20 tests with the cultivation of samples. heart, kidneys inside the body of pigs and sheep. Unfortunately, all had to stop before these parts were fully developed.

Last November, scientists presented the progress of this idea in a workshop at the National Institutes of Health and Health Research (Maryland). Accordingly, a University of Minnesota team used human stem cells to treat internal eye injuries in a pig fetus - based on the Chimera technique . As a result, when the piglet was 2 months old, it was completely cured. This is considered a perfect combination of genetic modification and stem cells - which are becoming hot topics in the scientific world today.

First of all, scientists use CRISPR gene editing techniques to refine pig or sheep cells so that these embryos develop certain body parts. The only obstacle is that these parts will be very difficult to survive if scientists do not take normal cells taken from another embryo implanted to compensate for the lack of genetic space. In the end, human stem cells will be introduced to create a hybrid of embryos based on other organisms, such as the formation of usable body parts.

Transplanted hearts on some animals can become lifesavers for many patients.

Biological doctor Hiromitsu Nakauchi of Stanford University said that pig cells and sheep cells normally have only 0.5% similarities with human cells but with genetic modification techniques and cell transplants. The root can be as high as 40% - this is a very positive basis for the human embryo culture of pigs or sheep. Even scientists have planned to bring human DNA into pig's DNA to increase the effectiveness of this process.

In fact, Chimera caught the attention of scientists in 2003, experts at Shanghai Medical University successfully combined human cells with rabbit's eggs. These are the first successful man-made Chimera models. They grow for several days in a laboratory dish before scientists destroy the embryo to get stem cells. Then in 2004, researchers at Mayo Hospital (USA) created lab pigs that possessed human red blood cells.

Chimera is a technique that combines DNA between two or more species in one body, sometimes referred to as cross genetic engineering.

For example, damaged heart valves are often replaced by weak heart valves taken from cows or pigs. This type of surgery was already carried out widely and in fact made the recipient turn into a Chimera. For years, scientists have also added human genes to bacteria or livestock to harvest valuable proteins in pharmaceutical production.

Chimera can create individuals with different colored eyes.

The creation of Chimera raises many questions: What do people create them for? Are individuals containing DNA considered to be human? If so, how will they be treated? According to scientists, animals are as human as possible because they are models for testing drugs or feeding parts for human transplantation. Monitoring adult cells and interacting in a living organism can also help professionals find new therapies.