IPS cells do not cause rejection in experimental mice

According to an article published online by the British scientific journal Nature, Japanese scientists found no rejection reactions in experimental rats after implantation of mature cells produced from the Multifunctional stem cells (iPS).

This new finding by a team of scientists from the National Radiation Science Institute (NIRS) and Tsurumi University (Japan) challenged the results of scientific research in an article published in the journal Nature in the year. 2011 by the University of California team of researchers when iPS cells cause an immune response in mice.

The prevailing view in today's regenerative medical experts is that the immune response does not occur in patients receiving fully differentiated cell transplants from iPS cells, the type of cells that are formed from the the patient's own cell.

Earlier reports by US scientists on iPS cell immunity attracted the attention of public opinion because it was contrary to the conventional view of scientists. Opponents of this finding doubt why the US team opted to transplant fully-differentiated cells - a method that will not be used in medical applications.

According to the new article, NIRS researcher Ryoko Araki and her colleagues created bone and bone marrow cells from iPS mice and implanted them into other mice along the same genetic traits.

Body and tissue transplantation methods are currently popular in modern health. However, the rejection of a transplant is the biggest cause of organ transplant failure. With the vigilance of the immune system, the body sees the strange organ as the 'enemy' and turns to attack the newly implanted 'strange' tissue.

In order to control this process, patients need to take anti-rejection medication. This treatment also causes many harmful side effects on the patient's body. New discoveries about iPS and the practical applications of this versatile cell technology in the field of health have really opened up a new direction for world medicine.