People will live to 110 years old?

Living long and healthy without using drugs or any assistance such as New York Sadie Kaplan (USA), about to pass 105 years old in June, is always the desire of mankind despite the secret of life Her long time is still unknown.

Kaplan's life-long secret is still a mystery.(Photo: MSNBC)

Together with 449 seniors over 95 years old, he lent genes to Yeshiva University to study the causes of aging. Through genetic analysis, experts found that women were as low as Kaplan (currently 1.52 m high, 1.57 m at a young age) that could carry a mutant gene related to longevity.

In addition to the longevity gene project just mentioned, anti-aging experts in the US are also pursuing many methods that they hope will one day help us to live. Here are the treatments being noticed:

Calorie restriction

For decades, the practice of eating less is considered a 'gold standard' to enhance life expectancy. A calorie-restricted diet (CR) is designed to help lower cholesterol, reduce the risk of cardiovascular diseases, inflammation and bring many other health benefits. The reason is that CR contributes to transforming essential metabolic enzymes, thereby producing new proteins and eliminating damaged proteins.

Through initial testing, this therapy helps increase longevity and reduce the risk of yeast, worms, flies, and mice diseases while helping to prevent heart disease, high blood pressure and high cholesterol. However, testing has shown that it is difficult to maintain 'very small' therapy from year to year and users are at risk of severe malnutrition. Moreover, the effects of CR on the immune system have not been determined.

Mimic CR

Medicines or dietary supplements that imitate the effects of CR without fasting are also useful, especially when they affect a range of proteins that govern the life of the organism. In humans, one of the key genes that regulate the metabolism mechanisms involved in aging is SIRT1. Last year, when Sirtris Pharmaceuticals introduced SRT501 to treat type 2 diabetes, experts found that the drug had an effect on the aging process by activating the SIRT1 gene and mimicking the effects of CR at the level. cell. The results of clinical trials on diabetics in India show that SRT501 is safe and does not cause side effects.

Impact at the cell level

Researchers favor two potential 'candidates' for insulin-like growth factors (IGF-1) and mTOR. IGF-1 controls a variety of hormones that promote cell growth during adolescence and last for a lifetime but to a lesser extent. Mutations will reduce the effectiveness of IGF1 and growth - a proven method to significantly increase the lifespan of worms, flies and mice. This complements the recent findings of Dr. Nir Barzilai, director of the American Institute of Aging Research, that mutations make people small but increase life expectancy, as is the case with Kaplan. The MTOR is a protein that regulates cell growth and proliferation. Recently, mTOR studies have also shown that 15 of the 25 genes that regulate aging in yeast and worms are also present in humans.

Telomeres, antioxidants and stem cells

Meanwhile, the international medical community is initially testing the method of protecting telomeres, the molecule protects two heads of chromosomes, because the older the body is, the shorter the size of the telomeres or the corrosive contamination. chromosomes are vulnerable and the body is susceptible to disease. Similarly, natural antioxidant therapy in fruits and vegetables helps to limit the damage to tissue and aging muscles, but the results are not satisfactory. There is also stem cell transplant therapy for anti-aging, but the research and testing process is not smooth due to the controversy and limitations surrounding the use of embryonic stem cells.

However, Dr. Barzilai confirmed biologically, one day, the average life expectancy of humans can be 10 years longer than the average age of 80 now, we can even live up to 110 year old. Not only that, people will also live better thanks to medical intervention from middle age.