There is going to be an alternative medicine for exercise
Scientists believe that we are getting closer to developing a drug that helps people who do not have to work hard but still enjoy the same benefits as exercise and sports.
A new study has found a compound that affects the levels of REV-ERB protein in muscles, helping to increase metabolism, normalize blood cholesterol levels and positively affect sleep duration. human.
According to the New York Times, scientists from the Scripps Research Institute in Florida, USA conducted injections of newly discovered compounds in obese mice, the results showed that the compound helped reduce experimental animals. weight even when still being fed a high-fat diet as well as improving their blood cholesterol levels.
Newly discovered compounds help increase metabolism, improve blood cholesterol levels and positively impact human sleep patterns such as exercise and sports.(Artwork: ABC News)
Compound mice also began to use more oxygen during the day and consumed about 5% more energy than other normal mice, although they did not move or move more. This implies, the compound has helped increase metabolism in experimental animals.
The Scripps Institute team also collaborated with colleagues at the Pasteur Institute in France and a number of other institutions to find out what their compounds could do inside the muscles to provide a physical workout effect. "invisible".
Researchers already know the compound that enhances the effect of REV-ERB protein , but it's unclear how it actually affects muscles. Therefore, they developed a protein-free mouse called REV-ERB that revealed a lot in their muscle cells and called it "anti-athletes".
One of the features of regular physical training is the increase in the amount and activity of mitochondria - the cellular structure that produces energy while absorbing oxygen in the muscles. However, the muscles of "anti-athlete" mice contain very little mitochondria, causing them to lose their resistance and target nearly 60% lower oxygen consumption than normal species of the same species. .
In experiments, the team added compounds to individual muscle cells of "anti-athlete" mice and found that these cells began to appear more REV-ERB proteins. Later, they also began to create new mitochondria and strengthen existing structures.
Thomas Burris, co-author of the study and currently chair of the Department of Pharmacology and Physiology at St Louis University School of Medicine (USA), explained that the compound "faked" the movement process. Experts hope, the compound could someday help disabled people enjoy the benefits of sports without movement.
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