There will be anti-aging medications due to sunlight

Excessive exposure to the sun is a leading cause of skin aging. Using sunscreen, collagen is just a temporary solution and not very effective. However, in the future, there will be a special drug that will help combat the aging effects of sunlight.

With a research discovered by accident, scientists at the University of British Columbia (UBC) are taking further steps in creating a special category that can prevent this phenomenon.

Made by a team led by UBC professor Davis Grandville, they went on to investigate and analyze the role of an enzyme called Grandzyme-B (the enzyme involved in many of the diseases in It has atherosclerosis and stroke.

Grandzyme-B works naturally in the human body, but if it exceeds the permitted level it can also cause immunity and destruction of collagen structure (an important component of human skin. ).

In the study, scientists found that if experimental mice lacked these enzymes, they would have higher resistance to diseases related to sclerosis and narrowing of blood vessels. At the same time, they also noticed that these mice had more smooth and rounded skin than some normal Granzyme-B species.

The researchers then went on to another experiment, but this time with two types of mice in artificial cages with sunlight. They are exposed to this type of light for 3-4 minutes and continuously 3 times a week. After more than 20 weeks of repeated exposure, the scientists found that mice with less enzyme Granzyme-B had healthier skin and still retained the most collagen pigments.

Granville said he and his team are actively developing a topical drug to inhibit Granzyme-B's activity (the main cause of the breakdown of collagen structure). Reportedly, the team will partner with microDA Therapeutics, a biotech company, to conduct tests on patients with disk lupus erythematosus, autoimmune disease . due to excessive exposure to light God. Estimated trial period within 2 years.

If the final test results on people are successful, in the future people will not have to worry about skin getting darker or aging faster when exposed to sunlight. In his research, sunlight is considered as the main factor that promotes the proliferation of Granzyme-B on the skin.

In addition to skin-based preparations, the application from this study also promises to open a new hopeful door for patients with unfortunate conditions such as aneurysms and chronic obstructive pulmonary disease ( It is caused by the breakdown of collagen in the blood vessels and lungs.

Reference: Gizmag.