Tracked the journey of HIV virus into the center of the cell

French researchers at the Pasteur Institute have for the first time succeeded in observing the journey of the HIV / AIDS virus to the center of infected cells, paving the way for therapies to prevent its infection.

French researchers at the Pasteur Institute have for the first time succeeded in observing the journey of the HIV / AIDS virus to the center of infected cells, paving the way for therapies to prevent its infection.

To do this, the researchers used fluorescence to mark a protein that came with the viral genome to enter a chromosome in the nucleus of the human cell. Then, thanks to microscopic film techniques, they followed the virus's journey inside the cell. At the same time, they used a sophisticated software capable of analyzing high-precision movements of virus particles, reproducing their journey in three dimensions in real time.

Picture 1 of Tracked the journey of HIV virus into the center of the cell
Source: BBC So Pierre Cherneau and colleagues have observed the interactions of the virus with infected cells, especially the means of transport used inside the cell.

Once inside the cell, the virus spreads everywhere. However, researchers lost sight of fluorescent protein.

According to bacteriologist David McDonald of the University of Cleveland, when identifying virus transport vehicles, the team took an important step in developing tools that can analyze detailed details. smallest in HIV infection.

These techniques can help find ways to prevent the spread of HIV.

Update 14 December 2018
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