Why do cancer cells spread abnormally?

The high number of receptors of cancer cells makes them more strongly interact with blood vessel walls, pushing through the vascular wall into surrounding tissues.

Our bodies are made up of trillions of cells. They have an activity called anastasis. Basically, when old cells die, new cells will replace them.

Cancer occurs when there are many abnormal cells that the body's immune system cannot handle promptly. Instead of dying, these abnormal cells continue to grow uncontrollably, thereby forming tissue tumors. Tumors continue to grow, called malignant tumors , that can spread to other areas. There are more than 100 different types of cancer and can develop in any type of cell in the body.

Picture 1 of Why do cancer cells spread abnormally?
Cancer cells have 200 times greater thrust than healthy cells.

Why do cancer cells spread so quickly? Scientists examine the strength of cancer cells through a device that simulates blood vessel walls, to understand the movement of cancer cells, how they coordinate invasion of other parts of the body . The deformation of the device is a measure of cell repulsion.

Dr. Joseph Ndieyira, of the University of London, said that both cancer cells and healthy cells have identical receptors on the surface, but cancer cells have much more receptors. This helps them coordinate to move through narrow blood vessels by forming a continuous network of cancer cells, clinging to the walls of arteries and arteries. When two or more cancer cells are linked, they tend to stretch, thin and weaken the cell walls of the vessels where they attach.

High receptor numbers also allow them to interact more strongly with blood vessel walls, thrusting through blood vessel walls into surrounding tissues such as motorways on highways. In particular, cancer cells can identify each other and distinguish themselves from benign cells , emitting mechanical signals that make metastasis faster. Since then malignant cells easily migrate to many different parts of the body.

"Cancer cells have 200 times the force of action, to push through the weak parts of blood vessel walls and narrow capillaries," Dr. Ndieyira said. Some cancers grow faster including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), breast cancer, and lung cancer.

Professor Massimo Pinzani, Director of the Institute of Liver and Digestive Health, Department of Medicine of UCL, commented that understanding the mechanism of cancer cell migration could consider studying methods to slow or prevent cancer. Spread.