Detects genes that regenerate hair and skin

American scientists at the University of Southern California have discovered a series of genes involved in hair and skin regeneration, in three studies published in Stem Cells and The Proceedings of the National Academy of Sciences.

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The new finding opens up the prospect of balancing baldness and regenerating skin.(Photo: Healthpedic)

First, the research team of Dr. Krzysztof Kobielak and colleagues found that the Wnt and BMP genes mark the path of hair growth cycle. Accordingly, when the signal path of BMP gene and signal path of Wnt increase, it will stimulate hair growth. Conversely, increased BMP signal and reduced Wnt signal will cause hair follicle stem cells (hfSCs ) to accept stop status.

In the next study, the scientists analyzed the function of two key proteins during the path signaling of BMPs called Smad1 and Smad5 - which activate signals to regulate stem cells to grow. new hair. The team also looked at how Wnt7b stimulates hair growth and finds that hair will stop growing when the gene is damaged.

From these studies, scientists concluded that hfCS has the ability to regenerate hair follicles . Dr. Kobielak said this finding not only leads to new treatments for baldness but also opens up the prospect of skin regeneration for burns and skin cancer patients.