Detects proteins that control immune system activity

Scientists at Johns Hopkins University have discovered a type of protein molecule called carabin that can suppress immune system protection. From this finding, scientists are finding ways to prevent immune responses

Scientists at Johns Hopkins University have discovered a type of protein molecule called carabin that can suppress immune system protection. From this finding, scientists are finding ways to prevent unwanted immune reactions.

Immunity is necessary for human life. The body always faces risks such as bacteria and viruses.

Picture 1 of Detects proteins that control immune system activity

The immune system must always cope with the emergence of bacteria and viruses.(Photo: SPL)

To protect themselves, the body's immune system is always mobilized to cope with the risks of disease. However, if the overactive immune system can be detrimental to the body. Therefore, the team led by Professor Jun Liu is looking for substances in the body that control the activity of the immune system.

They found a protein called carabin whose function is to limit the ability of cells to react to infection. Scientists found that when there is more carabin in a cell, the cell seems to control its own activity.

Professor Liu said, the protein acts as an internal suppression to reduce the speed and intensity of an immune response. As a result, the immune system's activity does not go beyond the control to attack " BLOOD " into healthy cells.

It's like having a built-in timer to keep your immune system in check. The aim of the study is to show how the immune system adjusts, thus finding the possibility of effective treatments for different forms of autoimmune diseases.

In some cases, it may be beneficial to cut carabin, not to increase it, for example in the early stages of HIV infection, when a strong and sustained immune response may be useful.

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Update 14 December 2018
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