Discovering 'gold' of 3 genes associated with breast cancer

Researchers have found three genes associated with the most common form of breast cancer. In particular, one gene plays a role in controlling the growth of malignant tumors.

These genes may open new directions in the diagnosis and treatment of endocrine breast cancer, the type of breast cancer that estrogen receptors work so positively and account for 4/5 cases of breast cancer.

Scientists from London's Center for Breast Cancer Research, the Institute for Cancer Research (ICR), said: ' This finding will help patients with breast cancer but do not respond to medications such as tamoxifen. "

They placed the genes C6ORF96, C6ORF97 and C6ORF211.

Dr. Anita Dunbier, in charge of research, said: ' This is a surprising finding because we found these genes where we believe we know very well .'

Dunbier and colleagues studied the DNA of 104 women with estrogen receptor-positive breast cancer, especially looking for genes closely related to these receptors. The results showed that C6ORF211 gene causes tumor growth. The presence of C6ORF97 shows that patients will respond to tamoxifen, a drug that interferes with estrogen activity. C6ORF96 alone has not identified the role.

Professor Mitch Dowsett, who led the study, said: 'This study is interesting because it shows that while estrogen receptors control the development of breast cancer, there are other factors that control it. . And understanding how they work will help us save many women with breast cancer . '