Discovering new proteins can destroy cancer cells

Cancer is always a horrifying terror for every person, we silently pray for a miracle or a remedy to heal this disease. And scientists in Australia have helped to light this belief with their research.

Scientists have found a new way to cause cancer cells to die, using their own cell self-cleaning mechanism . By exploiting the activity of a protein called Bak , known as a biological assassin that kills aging, aging cells, the Australian team has found a way to transfer killer proteins. this to cancer cells.

Researcher Ruth Kluck from Walter Eliza Hall Medical Research Institute, Melbourne, said: "They are just happy to find a completely new method of activating Bak."

Bak works in the body under normal conditions, the process of establishing cell death is called apoptosis . Apoptosis removes unwanted cells from the inside of the body, a decline in the process of causing cell death that allows cancer cells to grow uncontrollably or immune cells that attack the body.

Dr. Ruth Kluck from Walter Eliza Hall Medical Research Institute.(Source: Walter and Eliza Hall Institute of Medical Research).

Using Bak's three-dimensional structure information, the team discovered that a certain antibody could invade Bak proteins and activate it. This led the team to investigate whether they could control where the protein would attack.

Kluck said: "We are very interested in making drugs to activate Bak to treat diseases like cancer. This finding leads to a new beginning in the development of activation therapies. Direct Bak and destroy the cells ".

Scientists have also discovered a protein called BH3 protein that can be used to activate Bak. The next stage is to develop antibodies into a drug that can locate Bak in the cell and test it in living samples.

Autoimmune disease can also be treated with similar drugs. For autoimmune disease, an apoptosis incident also allows immune cells to attack the body so Bak can be used to destroy these cells. Research on cancer has gradually become interesting, scientists are gradually modifying the disease, discovering the ability to treat more effectively both chemotherapy and radiotherapy.

Since the nano-carrier (nano-carriers) system was invented to bring chemotherapy drugs directly into the brain to gain a deeper understanding of the cause of cancer, we are constantly striving to Find out deeply about the root of this disease. The research process now has more antibody activating Bak, this is a new hope for the scientists to try to develop and bring more potential.