Former Deputy Director of Hospital K indicated 4 causes of 80% of breast cancer cases

According to PGS, up to 80% of cancers in general and breast cancer are directly related to exogenous factors, especially the living environment.

Breast cancer is the leading cancer in women. This is considered the most dangerous disease for women and the incidence is higher and the factors causing disease are present righteous in the lives of women every day.

According to statistics in Vietnam in the early 2000s, this ratio was about 16 / 100,000 women, now this figure is 29 / 100,000.

Vietnam cancer recognition shows that large cities (Hanoi and Ho Chi Minh City) have a higher incidence than other provinces and cities (Thai Nguyen, Hai Phong, Hue and Can Tho).

The average age of Vietnamese women is significantly lower than that of developed countries. 50% of patients are treated for breast cancer in Vietnam around the age of 40-50, while in the United States around this age is 50-65.

Associate Professor Pham Duy Hien - Former Deputy Director of the National Hospital of K said that like other cancers, breast cancer has not found the cause but cancer research has shown that breast cancer factors very present in everyday life.

80% of breast cancer is related to lifestyle

Breast cancer is the leading cancer in women.

According to PGS, up to 80% of cancers in general and breast cancer are directly related to exogenous factors , especially the living environment. The proportion of women with high breast cancer in developed countries is a testament.

There may be modern lifestyles such as smoking, drinking alcohol, a diet high in energy and fresh fruits and vegetables and fiber.

The use of oral contraceptives, abortion, childbirth, breast-feeding, living and working in industrially polluted environments even with research showing light pollution (light pollution) is also increases the rate of breast cancer.

1. Tobacco : Active and active smoking also increases the risk of breast cancer. Studies from Europe and Canada have suggested that the earlier the age of smoking begins, the longer the smoking time, the more likely it is that smoking will correlate with breast cancer, the risk increases to 35- 50%.
2. Alcohol : So far, when it comes to alcohol, everyone thinks it only involves liver cancer, pancreatic cancer .

A study of 1.2 million middle-aged women in the UK concluded that if drinking 2 alcoholic drinks a day (1 unit is equivalent to 10 ml of spirits or 330ml of beer), the chances of getting cancer increase 8% more than women who only drink 1 unit per day. If drinking more than 2 units per day, this possibility increases by 1.1%.

Because alcohol stimulates the secretion of female hormones (estrogen & androgen) while 65-70% of breast cancer develops this endocrine dependency and increases the likelihood of breast cancer metastasis. Alcohol activates carcinogens that damage the mammary parenchyma. Alcoholic metabolites such as Acetethanol cause DNA damage to mammary cells.

1. Oral contraceptives : According to PGS Show if taking prolonged oral contraceptives, frequent over 5 years increases the likelihood of breast cancer by 1.5 times over 10 years, 2 times higher than non-users.

But if you stop taking it after 5 years, your chances of getting sick again will be as normal. In addition, women taking endocrine support at postmenopausal age over 5 years (Estrogene + Prolactine) are also at higher risk.

1. Eating : PGS Hien thinks that breast cancer, diet leading to obesity increases the risk of breast cancer.

Most patients with breast cancer have a body mass index (MBI) greater than 23. High-fat diets, lack of green vegetables, fresh fruits, lack of micronutrients are only available in whole grains, lacking iodine . causes high blood cholesterol index, diabetes is also a risk factor for breast cancer.

Lifestyle with less physical activity, working in an environment with radioactive contamination or being treated with radiation to the chest area also increases the likelihood of becoming ill.

Feeling endogenous factors

Breast cancer patients examined and treated at K Hospital 1.

In addition to exogenous factors, PGS Hien said endogenous factors are also important although it accounts for only 20% of carcinogenic factors.

Accordingly, for women with early menstruation (before 13 years of age for Vietnamese women, before 12 years for American women) and late menopause (after 50 and after 55 years of age respectively) are likely to have high breast cancer. more than others.

Similarly, women with first-born children after 30 years of age and who did not give birth for any time, do not breastfeed have a higher rate of breast cancer.

In addition, breast cancer is a type of cancer that is highly associated with genetics. Up to 5-10% of patients with breast cancer are related to genetics from generation to generation. Those with mothers with breast cancer are twice as likely to develop breast cancer as people in their 40-50 age group.

Genetic syndrome of breast cancer - ovary is mainly caused by mutations of BRCA1 and BRCA2 genes. This mutation is inherited for the next generation almost 100%, especially when the mother has both cancers.

Therefore, it is recommended that both of the mammary glands be removed before cancer when the mother has two cancers that test for mutations in the BRCA1 & 2 gene.