Genetically modified bacteria can prevent obesity

(Researchers, led by Sean Davies, of Vanderbilt University, have demonstrated that a genetically modified bacterium can prevent weight gain, even if it is still effective.) 1 month after stopping treatment. The results of the study were published in The Journal of Clinical Investigation.

According to Iflscience, no miracle supplement can help you lose weight effectively. At this time, there are many types of weight loss drugs approved by the FDA for its effectiveness in treating obesity and gastrointestinal diseases.

Researchers genetically modified a harmless strain of E.coli bacteria (Nissle 1971) to produce N-acylphosphatidylethanolamine (NAPE) compounds , which act as anti-appetite drugs . This bacterium is added to the drinking water of mice. These mice were fed high-fat foods for about 8 weeks. As a result, mice with genetically modified bacteria gained insignificant weight gain, consumed less food, and had less signs of obesity than mice that did not have genetically modified bacteria. Furthermore, mice containing NAPE-producing bacteria continued to show these positive signs for about 4-6 weeks after stopping treatment.

Human intestines contain about 100 trillion microorganisms, most of them originate in 40 different types. Many of them have positive digestive benefits and help eliminate pathogenic bacteria. In other words, this type of E.coli bacteria, known as a probiotic, can be cleverly used in weight loss. Unfortunately, several key changes need to be made before a human clinical trial can be performed.

Modified bacteria can resist antibiotics . This is the reason that it can be easily developed in the laboratory for research purposes. At present, there have not been any signs that it is harmful to humans, but researchers need to continue to find an alternative before it is used on humans. This alternative should be strictly tested to ensure that it is not harmful to health.

Obesity has become 'a pandemic' worldwide. It has killed 2.8 million people every year. Type 2 diabetes affects 347 million people globally, and over 80% of the world's population is diagnosed with obesity.