Is 'the elixir of life' inherent within us?

For thousands of years, people have had to go to every corner of the pool to find the eternal remedy. But according to the results of a scientific study, perhaps this 'remedy' is inherent in us.

After analyzing cell samples of super-minnows (those who lived over 110 years old), Japanese scientists discovered an interesting fact: These old men contain the amount of T cells CD4 (a type of immune cell) is much more than normal people. Perhaps it is the type of cells within our bodies that are the "elixir of life" , which people have been searching for thousands of years.

Elderly people have more CD4 T cells than normal people.

People who live over 110 years old are rare in the world. For example, in Japan, in 2015, the country of sunrise (which is famous for longevity) has about 61,000 people over 100 years old, but only 146 people over 110 years old.

Many studies done in the past have shown that the super-cypress group is linked to immunity to many diseases, typically infections and cancers, throughout life. This also means that the super-minnows will possess a strong immune system, and the recent research of this team has partly explained the factor that makes this wonderful ability.

Specifically, a team of researchers from Keio University Medical School (Japan) conducted an analysis of immune cells from the super-minnows and the control group was younger. In this experiment, the researchers collected a total of 41,208 cells from 7 superperfections (an average of 5,887 cells / person) and 19,994 cells from 5 people in the control group (an average of 3,999 cells / person). ) ages 5x to 8x.

The results of the analysis indicated that the number of B cells in the super-cypress group was lower but the number of T cells was almost the same as the control group. In particular, the number of a T-cell classification has increased in the super-cypress group. In-depth analysis of this classification showed that the super-cypress group possessed a superior number of toxic T cells (T cells containing cytotoxic cells capable of killing other cells). Even in some cases, the number of these toxic T cells accounts for 80% of the total number of T cells, compared to 10-20% in the control group.

Usually new CD8 T cells are capable of causing cytotoxicity and CD4 T cells do not have this capability. However, in the case of the super-minnows, the highly specialized toxic T cells are CD4. To find out how special CD4 T-cells in the super-cypress group are produced, the scientists analyzed blood samples from two super-cytosites and found that these cells were the result. of asexual fast multiplication (cells conducting mitosis create a large number of progenitor cells).

Dr Piero Carninci, a representative of the research team, said: 'Normally CD4 T cells will produce cytokines (a type of cell signal) and CD8 T cells will produce cytotoxic. In the case of the super-cypress group, special, very rare CD4 T-cells in normal people may be the source of their ability to fight many diseases, especially the onset of tumors. This finding has opened a new dimension of research into the longevity's ability to fight the disease.

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