Observe the interaction between proteins in living cells

A German research agency announced on Monday that it has successfully researched a new method that can conduct high-speed and large-scale observations of the interaction between two proteins in living cells in animals. breast.

Cell model.(Artwork: Internet).

This method will help scientists study proteins in living cells such as cellular proteins and viral proteins.

In the past, when observing the interaction between proteins in living cells, scientists need to spend a lot of time and energy and often use FRET technique to conduct observations on each cell. cells with fluorescence microscope.

The announcement of the Institute of Immunology and Virus Research Heinrich Pater, University of Hamburg, Germany on February 20, from a statistical perspective, observes the interaction between proteins in living cells by traditional methods. unconvincing and error-prone.

This new method when conducting FRET technique analysis did not use fluorescence microscopy but using fluorescently activated cell analysis method (FACS) to observe the group of live cells to be beaten. oil with fluorescent pigments.

Michael Schindler, in charge of the team, said the method could also be suitable for observing cell parts such as cell nuclei, cell membranes and cytoplasm.