Successful rearing of artificial heart muscle tissue is as real, and it is considered an invaluable specimen

Can you imagine the rapid growth of biomedical field in this era or not, especially regenerative medicine? So look at the images below, which is an artificial heart tissue being developed by scientists in the laboratory.

Each beat of this heart tissue is like a real heart tissue - making it both appealing and frightening.

Scientists have just cultivated an artificially beating artificial heart muscle tissue.

In their study, scientists cultivated stem cells and controlled them to turn into atrial tissue - two chambers above the heart that receive blood from the lungs and veins to pump into the ventricles. It can beat, express genes and react to drugs in the way a true atrium shows.

This means that this artificial tissue will become invaluable in the development and testing of drugs to treat many related heart diseases, most easily conceived atrial fibrillation that even Apple are interested when they develop Apple Watch Series 4.

The study was carried out by German scientists and published in Stem Cell Reports. In it they use multitouch sensors called hiPCSs to create artificial heart tissue.

hiPCSs are stem cells that can be generated directly from adult cells, which are not related to the embryo, so do not commit moral rules. Another great feature is that hiPCSs can grow infinitely, as well as develop into all kinds of cells in the body.

In this study, scientists have trained hiPCSs to develop it into cardiac muscle cells called cardiomyocytes. It has a 3D structure, can stretch to the beat of the heart, respond to drugs and electrical impulses.

Scientists have used a vitamin A metabolite called retinoic acid , to reprogram cells into a suitable, like form of the atria.

"This is the first time human atrial heart tissue has been created in the laboratory from infinite hiPSC sources , " said study author Marta Lemme from the University of Hamburg-Eppendorf Medical Center, Germany.

"This work is extremely useful for laboratories and the pharmaceutical industry. Because to test potential drugs we need to have an atrial model in the laboratory. And the first step is to create cells that resemble atrial heart muscle of humans ".

That's what the research team did. They even compared their artificial heart tissue with the patients' atrial heart tissue on a functional scale, and down to the molecular level.

In the future, these artificial cardiac muscles will be used to study arrhythmias, or irregular heart rhythms. It has many different forms, but the most common is atrial fibrillation - when the heart rate is irregular and sometimes very fast, the atria can vibrate up to 350 beats per minute even when you rest, compared to the usually just under 100 beats.

Atrial fibrillation can make you dizzy, breathless and tired. Treatment requires medication to control the heart rate or even surgery to remove part of the heart that causes abnormal beats.