Successfully recreates human ears from fat
Doctors at Great Ormond Street Hospital in London are aiming to reconstruct the faces of patients who need treatment with their own stem cells derived from fat.
(Doctors at Great Ormond Street Hospital, London) are aiming to reconstruct the faces of patients who need to treat with their own stem cells derived from fat.
The team has recently developed successful cartilage tissue and believes it can be used to 'build' the ear or nose for the patient. In the article published in the journal Nanomedicine, they said, the techniques used could revolutionize the treatment of many cases.
Experts in the field say, although there are many ways to regenerate cartilage, some may cause mutation or distortion.
Doctors want to treat Microtia cases (Ear Distortion Syndrome) , which prevents unexpected results such as: development is not complete or may be lost or altered.
At this point, children with the syndrome are usually taken with cartilage from the ribs, then sculpted by plastic surgeons, flexing the shape of the ear and eventually transplanting into the right position. However, this method is requiring repeated surgeries, as well as leaving permanent scars on the chest and cartilage in the ribs that are unable to recover.
Method from fat
Luckily, the team envisaged a new way to replace this ear regeneration. From a small fat sample taken from the patient's body, stem cells will be separated and developed.
An ear frame will be placed in the water containing stem cells, so that the cells then shape the shape and structure of the ear as desired. They continue to use a number of other chemicals to 'persuade' the transformation from ear to ear cartilage cells. These cartilage will then be implanted on the patient as a true ear shape.
This method, which initially yielded more results than expected, however, it needs to be tested even more about fullness before being used extensively in treatment.
One of the researchers, Dr. Patrizia Ferretti, interviewed the BBC: 'This method is done only through a single surgery, thus reducing pressure and stress on young patients, along with it has an ear structure that hopes to grow as children grow older. '
This technique helped Samuel Clompus, 15, who had an ear regeneration surgery.
Samuel after surgery to regenerate the ear
Mrs. Sue, Samuel's mother, said: 'They did not need to take cartilage from the side of my son'. She also showed great support and support for this new technique.
This alternative method, can also be used to reconstruct the nose for cancer surgery patients.
Doctors also added that they can replicate bones from the same original materials.
Dr. Ferretti said: 'It is clear that we are at an early stage of developing this technique, the next steps will be to improve material selection and build them further.'
Commenting on the study, Professor Martin Birchall, University of London surgeon said: 'If something is reborn in your body, it is continuing to change. using fat stem cells may be a good thing, but they have not yet concluded whether this is safe or not. '
According to him, to achieve the desired results, more safety tests are needed. however, this can be considered a viable alternative technique and offers many hopes for patients with ear or nose defects.
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