The formula for placental volume reduces the risk of miscarriage

To overcome the situation of very small placental stillbirths, Yale University School of Medicine researchers have developed a new method of measuring each other.

To overcome the situation of very small placental stillbirths, Yale University School of Medicine researchers have developed a new method of measuring each other, which provides nutrients and oxygen to the fetus.

Technological limitations today make doctors unable to control placenta growth, the supply of nutrients to the fetus. There are cases where the placenta is too small for the fetus to run out of food and oxygen and die in the womb - leading researcher Harvey J. Kliman, a specialist in obstetrics. He and his colleagues published the results in the August 3 issue of the American Journal of Perinatology.

Every year, fetal death, or stillbirth, stays in the uterus, affecting 30,000 pregnancies in the US alone.To date, there has not been any specific way to determine the amount of nutrients and oxygen that exist in each other at a specific time.

Kliman decided to conduct this study after finding that many pregnancies at the end of pregnancy were associated with small placenta. He argues that just as an obstetrician can use ultrasound to monitor fetal growth, or pediatricians can weigh and measure children's indicators to make sure they are growing. Normally, placental growth can be controlled in the same way.

Picture 1 of The formula for placental volume reduces the risk of miscarriage
Placental volume reduces the risk of miscarriage (Photo: xaluan.com)

When Kliman asked the maternity experts why they did not check the placenta during routine pregnancy ultrasound, the answer was always: the placenta is a curved structure that is difficult to measure.If they want to measure the actual volume of each other at a time, they must have an expensive device in hand, undergo intensive training and need more time for each measurement.

With the help of his father (Merwin Kliman), mathematician and electrical engineer, Kliman developed an expression that uses the maximum length, height and thickness of the placenta. Kliman and the Yale University team adopted this method after comparing the predicted volume calculated with their formula (EPV formula for short), using the data from the previous test. at birth, with the actual weight of the placenta immediately after the delivery is completed.

'We have shown that the expression that predicts the actual weight of the EPV placenta has an accuracy of up to 89%,' Kliman said. 'This method proved to be very effective in the second and third trimesters of pregnancy, the time when many pregnant women often perform pregnancy screening ultrasounds.'

In addition to formulating the above calculation formula, the group is also collecting EPV data from major centers around the world to produce major volume milestones, doctors can rely on these milestones to determine See if the placenta is at a moderate volume, or too small, or too large.'I hope that in the future the EPV test will be conducted periodically on pregnant women,' Kliman said.

Update 14 December 2018
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