The prospect of pertussis vaccine

Dr. Joel L Ward, USA, and colleagues studied the pertussis vaccination program for 2,871 healthy, voluntary people aged 15-65.

Volunteers were divided into two groups: group 1 vaccinated against pertussis and the second group not vaccinated with pertussis but vaccinated against A.

Pertussis caused by Bordetella Pertussis.

These patients were followed for two and a half years, paying special attention to the symptoms of pertussis for 5 days or longer. Test suction water from the nose and throat of patients who have just had pertussis, just measured pertussis antibody in serum. Among 2,871 volunteers, 1,391 were vaccinated against pertussis but were vaccinated against hepatitis A for comparison.

The results showed that the vaccine to prevent pertussis is safe and strong, causing many antibodies. Whooping cough vaccine prevents 92% of whooping cough . In the group not vaccinated with pertussis, the incidence of pertussis ranged from 0.7% -5.7%. The incidence of pertussis increases with the duration of pertussis, ie 370 to 450 patients with pertussis among 100,000 people / year. Acellular pertussis vaccine to prevent pertussis is effective against both children and adults.

Pertussis caused by Bordetella Pertussis. Whooping cough causes strong noise due to strong breathing. In the past, when there was no vaccine to prevent pertussis, there were about 5,000 to 10,000 deaths each year in the US alone.

Since the introduction of the vaccine, the number of pertussis deaths has dropped to 30 per year. Most children (under 1 year old) have pertussis (40%). Older children (15 years old) have less pertussis (15%). When having a whooping cough, the patient has flu-like symptoms such as runny nose, stuffy nose, mild cough and mild fever. A week or two later, a coughing, ragged, red-faced coughing, longer than 1 minute. After every whooping cough, the child inhales strongly or vomits.

Whooping cough or spreading B Pertussis is transmitted from one person to another by splashes or saliva when the patient coughs, laughs, or sneezes.

The incubation period is 7-10 days. Sometimes longer than 21 days. Patients must try to transplant B. Pertussis bacteria from phlegm or nasal discharge. Blood tests and X-rays are also required. Most have to be treated in the hospital because of the risk of pneumonia. More rare complications include ear infection, dehydration of the body. Children under 6 months of pertussis often have a higher risk of death.