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The extremely rare Progeria disease causes newborn babies to age with tremendous speed. For every 8 million children born in the world, one will encounter this evil disease.
The extremely rare Progeria disease causes newborn babies to age with tremendous speed. For every 8 million children born in the world, one will encounter this evil disease.
The most serious form is Hutchinson-Gilford progeria syndrome, first described by Dr. Jonathan Hutchinson in 1886, and Dr. Hastings Gilford did the same in 1904.
(Photo: English.pravda.ru) At birth, children have progeria syndrome with normal appearance like other children. However, within a year, their speed slowed down and they were faster and lighter than other children of the same age.
Despite their normal intelligence, these diseased children will develop a distinctive appearance with bald heads, wrinkled skin, a thick nose, a small face and head-sized jaws. . They also often experience symptoms that are usually only present in the elderly: stiff, dislocated and more serious than cardiovascular disease.
Some children with progeria are performed coronary artery surgeries to eliminate life-threatening complications. However, there is currently no cure for this situation. Children often die at age 13, due to stroke or heart attack.
In 2003, US researchers discovered that the cause was a tiny point mutation on a single gene. This gene encodes two proteins, lamin A and lamin C, which play an important role in stabilizing the inner membrane of the cell nucleus.
When a mutation occurs, it causes the gene to produce an abnormal form of lamin A. It is this abnormal protein that disrupts the inner cell membrane, causing bad scent on tissues that must support strong stresses, such as the cardiovascular system and muscles that support the bones.
Parents and siblings of progeria children are almost never affected by the disease.
T. An
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