Detecting protein helps prevent dengue

US scientists have discovered an antibody-synthesizing protein that plays a key role in preventing the replication of dengue parasites in the body.

>>>Against dengue fever is "stalking"

This finding opens up great prospects for research and development of vaccines to prevent this dangerous disease.

In a study published in the journal Science on May 22, scientists from the US National Institute of Allergy and Infectious Diseases analyzed blood samples from 453 2-year-old Tanzanian babies and distributed them. Currently a protein called PfSEA-1 is able to block the damage caused by dengue parasites after they enter the host's red blood cells.

Then, after injecting this protein into five groups of experimental mice, the scientists found that PfSEA-1 helps reduce the level of parasites entering the mouse body, while helping them survive longer. compared to those not vaccinated.

Dengue patients are being treated at La Mascota Hospital, Managua.(Source: AFP / VNA)

In addition, the researchers also analyzed plasma samples of 138 men aged 12-35 years living in areas with high rates of dengue fever in Kenya.

Results showed that those with synthetic PfSEA-1 antibodies had a 50% lower parasite concentration than those without these antibodies.

According to the study, the presence of PfSEA-1 protein helps the body produce and form antibodies that prevent cloning and dengue fever parasites from spreading throughout the body.

With the discovery of PfSEA-1, scientists hope to develop a vaccine to prevent dengue in the future, helping to reduce the number of cases and deaths from this dangerous disease.

Dengue fever is an acute infectious disease caused by malaria parasites. The disease is spread by mosquitoes that burn infected people and then spread the disease to healthy people through stings.

It is a common tropical disease, with more than 2.5 billion people in 128 countries at risk.

Symptoms can range from pain and fever to circulatory problems, coma and death.

According to statistics, each year there are more than 600,000 dengue deaths, mostly children living in areas bordering the Sahara in Africa. There is no vaccine available to prevent this disease.

One of the difficulties to develop vaccines is that there are 4 different strains of virus associated with this disease.

Those who have recovered from a disease caused by a virus are immune for life, but only for that virus.