Find out how to treat obesity
Researchers at the Washington University School of Medicine have found a way to treat diabetes and obesity, the study was published in the August 2 issue of Cell Metabolism.
The study was conducted by disabling target proteins in mice, making them sensitive to insulin and less likely to be obese even when fed high fat.
Scientists have studied how the body produces fat from carbohydrate-containing food sources. That process requires an enzyme called fatty acid synthase (FAS).
They conducted experiments on mice without FAS in the cells. As a result, despite eating high-fat foods, they do not become obese.
The author of the study, Mr. Irfan Lodhi, said that mice without FAS on the body were more resistant to obesity than those with normal FAS in the body.
And he also said that the mice were not obese, not because they ate less than other mice but that they converted those fats into heat.
To understand why that happened, researchers analyzed fat cells of mice. Mice have two types of fat: white fat and brown fat.
White fat helps store excess energy leading to obesity, while brown fats help burn calories and fight obesity.
In genetically altered mice, synthesizing fatty acids in cells, the researchers found that white fats were gradually converted into brown fat-like tissues.
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