Hunger-causing hormones increase life expectancy

Diet prolonged lifespan. That is the result of many research projects. Yet scientists at the Southwest Medical Center of the University of Texas (USA) have found a simpler method, no need to apply a special diet.

The scientists have created genetically modified mice that live much longer than their counterparts: 30% in male mice and 40% in female mice. That is, if the normal lifespan of the mice is 3 years, the mice are 'allowed' to live for 4 years.

Liver cells shelter the 'locked-up temple of life' - hunger-causing hormones. (Photo: David Mccarthy)

That 'miracle' is that: The bodies of genetically engineered mice produce larger amounts of normal growth factors of fibroblast number 21 ( fibroblast growth factor-21 , abbreviated as FGF-). 21). This protein increases the cell's sensitivity to insulin and inhibits the effect of another growth factor, FGF-21, a substance that is much more likely to become a cause of many diseases, including cancer letter.

Research by the scientists also showed that if put into the body of obese mice FGF-21, it will help mice 'throw away' excess volume. If the amount of FGF-1 is greater than normal it is called a "hunger hormone" by forcing the body to burn excess calories. It is located in the liver cells and when the most productive sprouts will cause hunger.

In the work published in the journal eLife, the authors also reported that mouse lifespan increased significantly with increasing FGF-21 content regardless of their diet.

This makes FGF-21 extremely attractive. An arrow at the same time shot and killed 3 rabbits. It both reduces weight and prolongs life while maintaining a predetermined diet into a habit.

But, unfortunately, it causes side effects. Overdose, it causes infertility for female mice and dilutes the bones of both female and male mice. Therefore, in each case, the dose must be determined so that side effects do not appear.