Prevention of disease from the fetal stage
Scientists at the University of Toronto, Canada and Dai Brown, USA, have discovered that adult germs may have occurred during the fetal period.
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But if the tendency for a specific disease or health problem occurs in the fetal stage, before people choose bad eating habits or skip exercise that is healthier than sitting in a row hours on the couch. In other words, what happens if the outline of a person's future health map is drawn while still in the womb.
The current trend in medicine is to promote the study of fetal stage conditions , everything from nutrition to environmental toxins that mothers can be exposed during Pregnancy, can affect the rest of the life of the unborn child.
The field of study of the developmental origin of health and disease, based on that premise, depends on the environment in the womb, via genetic or physiological changes to prepare the fetus to adapt to the Specific conditions await them in the outside world.
However, these changes can cause significant and long-term consequences that scientists have just begun to learn.
" Studying the source of development of health and disease is a very interesting field of science and I think there will be a lot of people participating in this field in the next decade ," according to Kim Boekelheide, professor. pathologist and medical examiner, working at Brown University, in Providence, RI, USA.
Scientists studying this area also face many challenges. It is difficult to study what affects the fetal stage to the life of an adult later because this requires monitoring and studying a group of people from the fetal stage until this group of people die. The effect of low nutrition or pesticide exposure in mice still in the fetal stage, for example, may not accurately reflect the results for a fetus in humans.
" Research in this area is very difficult, " Dr. Boekelheide said.
However, scientists are still looking for new ways to deepen research in this area. Dr. Boekelheide and colleagues placed human tissue from a fetal spontaneous abortion, into animals to study the effects of exposure to different environmental factors.
Although the field of research into the developmental sources of health and disease has only been developed for decades, it has recently attracted an increasing number of attention, as researchers receive The prenatal and immediate birth conditions may have connections to the trajectory of an individual's lifelong health.
Stephen Lye, professor of obstetrics and gynecology at the University of Toronto, Canada, and deputy director of the Samuel Lunenfeld Research Institute, at Mount Sinai Hospital, Canada, received the Connaught Global Health Challenge Award. With a $ 1 million grant, it will allow Professor Stephen Lye and his colleagues to establish the Institute for Human Development, to find out how the environment in the fetal period can affect her health. baby throughout life later.
At the same time, Brown University, USA, also announced that it is establishing a research center, led by Dr. Boekelheide, to study certain conditions in the fetal period that may affect the fetus in Parts such as lungs, liver and prostate tissue.
One of the pioneers of this field, British researcher, David Barker, helped set the stage for studying the origins of health and disease development, with the results of his research in the years. 1980 and 1990 showed that babies born with low birth weight face higher risk of developing coronary heart disease. Dr. Barker's theory says that a fetus with a limited supply of nutrients can lead to priority brain development and a lower priority to help the pancreas, kidneys and other organs develop. development, may lead to more sensitive conditions for the baby's illness even in the decades after.
Other important research shows that women who experience high levels of stress during pregnancy are more likely to be the children of these mothers, becoming anxious or unconsciously fearless in their pregnancy. behavior, awareness. Researchers believe this is due to high fetal exposure to cortisol stress hormones.
Experiencing certain conditions in the fetal stage can also provide lifelong protection for children. According to research presented at the leading breast cancer research conference, Era of Hope, played in Orlando, Florida, USA in August 2011, the study results showed that the pups in fetal stage but Maternal rats consume high levels of fatty acids and nutrients such as folic acid and vitamin B12 during pregnancy may lead to some lifelong breast cancer protection effects for pups. .
It is sad to know that some people may have brought the germ of specific illnesses before they were born. However, scientists believe that if they can understand the complex interaction between genes and the environment and conditions in the fetal stage leading to genetic modification or other problems, to one day in In the future, scientists can develop preventive measures to minimize negative consequences.
For example, with a better understanding of the nutrition of the poor in pregnancy can affect the fetus can lead to improvements in prenatal health education programs as well as programs. Other to help women with low income or disadvantaged.
" There is nothing to doubt that we can significantly improve health, academic ability and social performance, if we invest more in maternal health care. babies are pregnant and children are still in the womb ", according to Dr. Lye.
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