Use highly elastic biological materials to regenerate bone

Northwestern University researchers have invented an artificial biological material that stimulates bone regeneration when transplanted into a patient's body.

This new method is not only simple but also affordable, opening new hopes for orthopedic surgery.

According to research results published in the American Translational Medicine magazine, this biological material is called highly elastic bone (Hyper Elastic Bone - HB) with a major component of ceramic containing inorganic substances. teeth and bones, and plastic.

Scientists have implanted HB into the spine of mice and the Indochinese macca skull. The first experimental results showed that after being introduced into the body of mice, HB quickly joined the tissues around it, thereby regenerating the bone and promoting spinal growth in mice.

Picture 1 of Use highly elastic biological materials to regenerate bone
Bone has high elasticity.(Source: theverge.com).

Meanwhile, in the second experiment, four weeks after transplanting the 3D printed piece of HB filled the hole in the Macca monkey's skull, the scientists observed that the gaping wound was filled and not available. signs of infection or other side effects. They even saw bone regeneration.

According to scientists, HB has many advantages over conventional bone implant methods. With the above composition, this biological material has better elasticity, safer than implant bone, does not cause harm when implanted into the patient's body.

Besides, the cost of making this material is less expensive, and especially based on the treatment needs of patients, scientists can use 3D printing method to create many shapes and cuts for This biological material.

Expected, HB will be tested on humans in the next 5 years. Ramille Shah, one of the authors of this study, said this work could become a future breakthrough in the field of orthopedic surgery, pediatric surgery and jaw bone when this new biological material Help revive bone.

Researchers hope that HB will soon be put to treat human bone injuries, including the spine, teeth, and bone marrow cancer surgery because this biological material is not only produced but also access to many patients.