Amniotic fluid for bone aging

UK scientists have published a report showing that cells in amniotic fluid surrounding the developing fetus can regenerate aging and weakening bone cells.

This finding can greatly support babies with genetic diseases, the elderly and even astronauts.

According to the study, astronauts can get osteoporosis at a rate of 1% per month, making the bones brittle and brittle when returning to Earth.

In mouse studies, the use of cells extracted from amniotic fluid helped strengthen softened bones and prevent fractures by up to 80%.

The fetus is in the womb of the mother, surrounded by amniotic fluid. Amniotic fluid helps protect the fetus, provides nutrition for growing babies.

Amniotic fluid is a nutrient-rich environment, capable of regenerating and exchanging, playing an important role in the survival and development of the fetus. Amniotic fluid appeared from the 12th day after conception, made up of three sources: fetus, amniotic membrane and maternal blood.

Amniotic fluid also contains stem cells. This is the origin of tissue development. The special function of stem cells is to create all other types of cells in the body.

Amniotic fluid may become a good source of anti-osteoporosis in the future.(Photo source: BBC).

Stem cells are considered new "suppliers" of cells. When stem cells divide, it can create new stem cells, or create other types of cells. For example, skin stem cells can produce new stem cells of the skin, or cells with special functions such as skin pigmentation.

Researchers collected stem cells from amniotic fluid during pregnancy or collected immediately before birth.

The team at the Institute of Child Health in partnership with Great Ormond Street Hospital and University College London (UK) injected these cells into mice with brittle bone disease or brittle bone disease.

In humans, this disease occurs at a rate of 1 / 25,000 births and can be fatal because it causes babies to be born with multiple fractures.

Even for survivors, they also face more than 15 broken bones each year, brittle teeth, impaired hearing and growth problems.

Osteoporosis is an increase in bone porosity due to a decrease in the amount of bone organization, a reduction in the weight of a unit of volume, as a result of the decline in protein frames and calcium intake associated with these frames.

Osteoporosis is also a consequence of the disruption of the normal balance of two bone formation and bone breakdown, the process of bone formation deteriorates while the normal bone destruction process.

According to the report of the World Osteoporosis Association (IOF), currently, the cost of treating osteoporosis is equivalent to treating diabetes and greater than the cost for both the most common cancers in women. Women combined (breast cancer and uterine cancer).

The biggest cost for osteoporosis is the treatment of fracture complications, especially femoral neck fractures.

Tests in mice show that injecting these cells increases the strength, toughness and bone structure of animals. The number of broken bones decreased to only 1/5 of the original level.