Are people about to regrow their limbs like salamanders?

Researchers claim to have found a new stem cell therapy, which can help people re-grow lost limbs or parts like lizards.

Lizard is a reptile that can regenerate the bones and tissues in the body when they are destroyed. A research team from the University of New South Wales (Australia) has discovered a way to mimic this lizard's great ability, based on "touch-sensitive stem cells" (iMS).

The team created iMS cells by reprogramming bone and fat cells. Theoretically, these cells can be used to repair and restore bone, cartilage and muscle.

The team created iMS cells by reprogramming bone and fat cells.

Professor John Pimanda, the head of the study, explained: "We are currently evaluating whether human fat cells after reprogramming into iMS cells can certainly restore damaged tissues. In mice or not, human tests are expected to begin at the end of 2017. The technique is groundbreaking, because iMS cells regenerate many different types of tissue, we took bone cells. and fat, disrupting their memory and transforming them into stem cells, so they can repair different types of cells, once returned to the human body. "

Until now, experts studying reconstructive treatments tested embryonic stem cells (ES) and induced pluripotent stem cells (iPS). Both types of cells behave in a similar way, multiply indefinitely and are able to transform into any type of body tissue. While ES cells are natural, extracted from early stage embryos, iPS cells are artificial products through reprogramming of adult cells.

Both types of cells contain the risk of creating cancerous tumors. In particular, iPS cells are born using the injected virus genes, a clinically unacceptable thing.

However, iMS cells in the new study are more limited but are thought to be safer than ES or iPS cells. Australian researchers have produced them by inhibiting "flexibility" in bone and fat cells from mice and donors. This technique involves exposing cells to a compound called AZA as well as a platelet- derived "growth factor" (growth stimulant).

AZA compounds set to loosen cell connections.

AZA compound establishes loosening of cellular connections, which are already expanding due to the growth factor. This transforms bone and fat cells into iMS cells. When these stem cells are injected into the damaged tissue area, they multiply, pushing growth and healing. This process is very similar to the lizard process that takes advantage of cell flexibility to regenerate broken limbs or tails.

Dr. Vashe Chandrakanthan, who developed the technology, said the method is more advanced than any other undergoing stem cell therapy. He and his colleagues said that this therapy has great potential in treating back pain and neck pain, spinal injury, muscle and joint degeneration as well as can promote the following recovery. Complex bone and joint surgeries.

Experts even expect, in the future, this method can be completed to help people re-grow lost hands, feet and body parts, meaning ending the existence of the organ transplant surgery.