Cautious when using analgesics, anti-inflammatory Nimesulide

Department of Health of provinces and cities, hospitals under the Ministry of Health inform treatment units of adverse reactions to patients taking Nimesulide.

On August 14, the Vietnam Drug Administration announced that the Department has just issued a request to the Health Services of the provinces and cities, hospitals under the Ministry of Health informing the treatment units of the reaction. harm to patients taking Nimesulide.

The treatment units should monitor cases of Nimesulide treatment, reporting adverse reactions to the Northern Center for Adverse Reaction Monitoring or the Drug Information Center and monitoring the Southern ADR. Doctors must carefully consider when prescribing drugs containing Nimesulide for patients.

Nimesulide anti-inflammatory drugs.(Photo: Pymepharco)

The reason why the Vietnam Drug Administration must issue the above notice is that the Department has received notice from the World Health Organization (WHO), the European pharmaceutical organization about the pharmaceutical authorities of Ireland and Singapore. Notification of total registration of all oral Nimesulide-containing products is due to the risk of hepatotoxicity.

In Vietnam, in 4 years (2003-2006), the Center for Adverse Drug Reactions also received 18 reports of Nimesulide adverse reactions such as anaphylaxis, itching, rash, difficulty. breathing . however there are no reports of adverse reactions to the biliary system.

Nimesulide has all three anti-inflammatory, analgesic, antipyretic properties, selective inhibitory effect on cyclo-oxygensae-2 reduces prostaglandin synthesis associated with inflammation. Nimesulide is indicated for the treatment of inflammatory and painful conditions such as osteoarthritis, post-traumatic and post-operative pain relief, bursitis, tendonitis, sore throat and dysmenorrhea.

Le Ha