Stop vaccination with Priorix vaccine is deadly shocking

Ho Chi Minh City Department of Health urgently requested medical units in Ho Chi Minh City to immediately stop the vaccination with Priorix to prevent measles-mumps-Rubella from GlaxoSmithKline.

Priorix pills
(Photo: greencross)

6 children in District 5 suffered from severe vaccine shock, including 1 death.

In addition, the Department of Health has sent a written request to GlaxoSmithKline to cooperate with the health sector and authorities to find out the causes of cases of complications after Priorix vaccination in children.

The accident

Until 14:00 on 11-5, at the Department of Resuscitation - Children's Hospital 1 still has 5 children in a state of mechanical ventilation. These are children who have had a shock after receiving Priorix vaccine against Mumps-Rubella.

Earlier, on the evening of May 10, 13-month-old Nguyen Thien Bao died of a drug shock after being vaccinated on May 9 at the Medical Station of Ward 9, District 5, Ho Chi Minh City.

Another case was baby Or Chi Vinh, 16 months old, vaccinated with Priorix on May 8 at ward health station, Ward 8, District 5. But on May 9, Vinh was taken to Children's Hospital. 1 in high fever, cyanosis and body edema. Currently, Vinh's condition is still in serious condition and doctors of Resuscitation Department of Pediatric Hospital 1 are facing shock and letting him breathe.

After being informed, the Department of Health requested all medical units in Ho Chi Minh City, especially District 5 Medical Center, to suspend vaccination of Priorix vaccine from GlaxoSmithKline and proceed. inventorying and sealing the above-mentioned vaccine lots.

At the same time, health units surveyed about the health situation of children within the past week have been vaccinated with this vaccine.

Besides, Ho Chi Minh City Preventive Medical Center organizes a sample of this vaccine shipment to test according to the prescribed process.

Anaphylaxis?

Doctor Le Thanh Chien, deputy director of the Tropical Hospital said, all vaccines for epidemics when put into human body are at risk of causing drug shock (called anaphylactic shock).

The mechanism of causing drug shock is caused by antibody antigen reaction.However, in the case of Mumps - Measles - Rubella vaccination, this rate is not much.

In some medicines, the manufacturer recommends "skin" tests before injecting into humans, but the vaccine usually does not have this recommendation.

Meanwhile, Dr. Nguyen Huu Duc of Ho Chi Minh City University of Medicine and Pharmacy is also very cautious when referring to the causes of severe shock after vaccination against Mumps - Measles - Rubella in The above pediatric patients.

According to him, if it is anaphylaxis, it can happen at any time and with anyone, even though there was no previous history of allergy. This is an unpredictable phenomenon.

In particular, TS. Germany stressed that the vaccine is a biological product, meaning from what is biologically (or foreign proteins), the easier it is to cause anaphylaxis and lead to death than any other. a medicine product.

Anaphylaxis (also known as anaphylaxis) is a very severe allergic reaction when the body comes into contact with an allergen (also called an allergen or antigen). And when this allergic reaction occurs if it is not detected and handled promptly, the patient can die.

Common causes of anaphylaxis are medication use, especially in the form of injecting drugs. Some drugs are at high risk of shock when administered as Penicillin, Streptomycin and some other antibiotics, only 1-2 minutes later are cyanosis, tracheal spasms, rapid pulse, respiratory failure, and cardiovascular collapse, hypotension, coma and possibly death if not timely emergency.

Dr. Nguyen Huu Duc explained that one of the biological substances called histamine plays an important role in anaphylactic shock. Normally, histamine is concentrated in white blood cells (especially mast cells, also called cells) and combined with another biological substance, heparin does not show any toxicity. Only when the body experiences an allergy (like a drug) will an antibody develop against it.

The reaction between the antibody and allergy is so intense that it causes confusion, the cell containing the histamine-heparin complex stimulates the release of free-form histamine and causes severe symptoms called anaphylactic shock.

Patients with anaphylaxis need to be treated firstly, first injecting adrenalin (to raise and maintain blood pressure), glucocorticoid drugs (such as methylprednisolon), antihistamines (such as promethazine) to treat allergies, oxygen breathing and ventilation good.