Tobacco causes genetic changes

Recently, in the Journal of Cancer in the UK, researchers believe that the main harm to tobacco is to alter genes and cause lung cancer.

According to the researchers, smoking makes the production of FANCD2 protein in lung cells very slow, while this protein plays a key role in restoring damaged DNA and Eliminate toxic cells that can cause cancer.

By replicating a lung of smokers, the team monitored the effects of smoking on other proteins in the cells. They found that the FANCD2 level was too low and the DNA could be destroyed at any time. FANCD2 is an important factor in the 'family' of proteins related to anemia. People who fall into this condition often lack protein and may develop malignant tumors at a very young age.

Researchers suspect other proteins also play a role in DNA repair and elimination of harmful cells. However, they also showed that lung cells with high levels of FANCD2 will have good resistance to the harmful effects of tobacco. Therefore, this protein is arguably the most important.

The results of this study increase the hope of improving the treatment of lung cancer. Dr. Laura Hays said this result showed the important role of FANCD2 in protecting lung cells from the effects of tobacco and explaining why tobacco is harmful to these cells.

According to Dr. Lesley Walker, director of cancer information at Cancer Research UK, smoking is the biggest cause of cancer and 9 out of 10 cases are cancer. lung. However, after 5 years of quitting, the risk of cardiovascular disease will be halved in smokers, and after 10 years the risk of lung cancer may be halved.