Successfully cultivate human intestinal tissue on mice

Scientists have successfully cultured human intestinal tissue on mice. This is a breakthrough step that can help cure thousands of patients with intestinal disorders.

By transplanting cells from humans into mice, scientists from the Los Angeles Children's Hospital School (USA) have successfully cultivated fully functional intestinal tissue as intestinal tissue in humans. The team hopes their findings will help treat a variety of digestive diseases as well as increase survival rates for patients with short bowel syndrome .

Scientists have successfully cultured human intestinal tissue on mice.

In the 2011 study, the team of scientists led by Dr. Tracy Grikscheit successfully raised human intestinal tissue in mice. But the intestinal tissue produced has a limited function, while intestinal tissue in the latest study demonstrates that it can disrupt the sugar-glucose binding and gastrointestinal hormone release.

Mice were selected in this study because mouse intestinal tissue has many characteristics similar to human intestinal tissue. For example, both contain stem cells capable of reproducing intestinal tissue.

Scientists took cells from human intestinal tissue and soaked them in digestive enzymes. A polymer frame is used to help cells and tissues grow. Then, it gets into the rat's body to develop intestinal tissue in 4 weeks. The team found that the intestinal tissue that is cultured can convert sugar into glucose.

'We can breed more complicated intestinal tissue than the original newspaper that is currently used to study intestinal diseases and its resilience. The intestinal tissue of plants proves to be fully functioning as intestinal tissue from human cells , 'said Dr. Grikscheit.

The study results open opportunities for people with intestinal diseases, especially short intestinal diseases. The intestinal tissue that is raised someday can be used to replace the grafting method and can solve the problem of lack of donors.