Successfully transform cancer cells into normal cells

American scientists turn cancer cells back to normal by returning it to the process of blocking cell replication - an important process that inhibits cell replication too quickly.

America turns cancer cells into normal cells

According to the Telegraph, reprogramming cancer cells , turning it into cells is often a breakthrough research step, promising new treatments, even reversing tumor growth.

Cancer cells stop dividing when the scientists put the brakes on.(Photo: Wellcome Collection)

Breast, lung and bladder cancer cells were first transformed into harmless cells, by restoring cellular functions that prevent them from replicating and overgrowth.

According to scientists at Mayo Hospital, Florida, USA, this is like using a braking system for speeding cars.

Research has so far been done on human cells in the laboratory, however, researchers hope, the technique will soon be used to treat melanoma , "turning off" cancer that causes the disease. The patient does not need chemotherapy or painful surgery.

"We can reconstruct the braking system and restore benign cell function," said Professor Panos Anastasiadis, Department of Cancer Biology.

"Initial testing on some cancers is very promising," he said. " It shows a new biological method, provides code, software to stop cancer."

Usually, cells divide continuously to create new cells instead. However, for cancer cells, ceaseless division leads to a large increase in cancer cells, causing tumor growth.

The scientists found that the glue that adheres to the cell is regulated by a microprocessor called microRNAs . When everything is normal, microRNAs tell the cell to stop dividing when enough numbers have been copied. They command through activation of PLEKHA7 protein production - proteins that break cell bonds. However, cancer cells do not occur this process.

" We currently experiment on human cells with breast cancer and bladder cancer, " said Dr. Anastasiadis. "These cells lose PLEKHA7. Restore the levels of PLEKHA7 or microRNAs in these cells, making them return to their normal state. We are investigating a more effective reconstruction method."

Cancer experts in the UK say that the study has solved the question of causing biologists to suffer headaches for decades, why cells do not prevent cancer cells from growing naturally.

"This is a great discovery, " said Dr. Chris Bakal. He is an expert in malignant deformed cell research, London Cancer Research Institute.

Henry Scowcroft, senior scientific manager of the British Cancer Research Program, said this important research has solved the long-standing biological mystery. This is an important step to find out how certain cells work in the human body. This knowledge is the key to continuing research on cancer treatment.